The museum consists of preserved biological and zoological specimens, wood samples; by-products of microorganism, and also thousands of living plants/trees maintained in a separate location. This museum also serves as a reference for science and a center for documentation, research, and information. It has a diverse collection of almost 500,000 preserved Philippine animals, plants, cultures of living microorganisms, and other biota that showcase the country’s rich biodiversity. It houses most of the priceless collections of birds and small mammals of the late Dr. Dioscoro Rabor, and has in its hortorium a diverse collection of living plants.
The UPLB Museum of Natural History main building stands inside the upper campus of the University of the Philippines Los Baños, at the foothills of Mount Makiling. Old records point out that prior to being occupied as a museum, the building used to be a laboratory station of the then Bureau of Forestry. The building now houses the Museum’s Integrated Biodiversity Exhibit, a preferred tourist and educational destination by schools and universities in the CALABARZON region.